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Index > Protein center > ZC3H8(Gene name) > Human
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  • ZC3H8 (Gene name),
  • Zinc finger CCCH domain-containing protein 8 (Protein name ),  ZC3H8_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ZC3H8(ZC3HDC8);
    Protein name:
    Zinc finger CCCH domain-containing protein 8;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    291
    Sequence:
    50:
    MDFENLFSKP | PNPALGKTAT | DSDERIDDEI | DTEVEETQEE | KIKLECEQIP | 
    100:
    KKFRHSAISP | KSSLHRKSRS | KDYDVYSDND | ICSQESEDNF | AKELQQYIQA | 
    150:
    REMANAAQPE | ESTKKEGVKD | TPQAAKQKNK | NLKAGHKNGK | QKKMKRKWPG | 
    200:
    PGNKGSNALL | RNSGSQEEDG | KPKEKQQHLS | QAFINQHTVE | RKGKQICKYF | 
    250:
    LERKCIKGDQ | CKFDHDAEIE | KKKEMCKFYV | QGYCTRGENC | LYLHNEYPCK | 
    291:
    FYHTGTKCYQ | GEYCKFSHAP | LTPETQELLA | KVLDTEKKSC | K
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Zinc finger CCCH domain-containing protein 8
    Cat.:
    E15467h
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Zinc finger CCCH domain-containing protein 8
    Cat.:
    E15467m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Zinc finger CCCH domain-containing protein 8
    Cat.:
    U15467h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Zinc finger CCCH domain-containing protein 8
    Cat.:
    U15467m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Zinc finger CCCH domain-containing protein 8
    Cat.:
    P15467Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Zinc finger CCCH domain-containing protein 8
    Cat.:
    P15467Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Zinc finger CCCH domain-containing protein 8
    Monoclonal Antibody for Human Zinc finger CCCH domain-containing protein 8
    Protein for Human Zinc finger CCCH domain-containing protein 8
    Protein for Human Zinc finger CCCH domain-containing protein 8

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Mammalian Ssb proteins related to ovarian development and differentiation."
      Zhuang D.Z. , Gunnarsson D. , Toffia O. , Lind M. , Lundgren P. , Selstam G.
      Submitted (2001-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Skin.
    3. 3.
      "Regulation of thymocyte homeostasis by Fliz1."
      Hwang E.S. , Ho I.-C.
      Immunology106:464-469(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    4. 4.
      "Transcriptional regulation of GATA-3 by an intronic regulatory region and fetal liver zinc finger protein 1."
      Hwang E.S. , Choi A. , Ho I.-C.
      J. Immunol.169:248-253(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    5. 5.
      "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
      Matsuoka S. , Ballif B.A. , Smogorzewska A. , McDonald E.R. III , Hurov K.E. , Luo J. , Bakalarski C.E. , Zhao Z. , Solimini N. , Lerenthal Y. , Shiloh Y. , Gygi S.P. , Elledge S.J.
      Science316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-77;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic kidney.
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-77;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    7. 7.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    8. 8.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-32;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 10.
      "The little elongation complex functions at initiation and elongation phases of snRNA gene transcription."
      Hu D. , Smith E.R. , Garruss A.S. , Mohaghegh N. , Varberg J.M. , Lin C. , Jackson J. , Gao X. , Saraf A. , Florens L. , Washburn M.P. , Eissenberg J.C. , Shilatifard A.
      Mol. Cell51:493-505(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;IDENTIFICATION IN THE LEC COMPLEX;INTERACTION WITH ICE1
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